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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

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Related Experiment Video

Updated: May 16, 2026

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
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Published on: May 30, 2011

Brain perfusion imaging: How does it work and what should I use?

Blake E McGehee1, Jeffrey M Pollock, Joseph A Maldjian

  • 1Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA. bemcgehee@gmail.com

Journal of Magnetic Resonance Imaging : JMRI
|November 21, 2012
PubMed
Summary

Magnetic resonance imaging (MRI) techniques for cerebral perfusion have rapidly advanced. This review guides clinicians in selecting the optimal MRI perfusion method for specific clinical scenarios.

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Area of Science:

  • Neuroimaging
  • Radiology
  • Medical Imaging

Background:

  • Cerebral perfusion imaging is crucial for diagnosing and managing various neurological conditions.
  • Recent years have seen significant advancements in magnetic resonance imaging (MRI) techniques for assessing brain blood flow.

Purpose of the Study:

  • To review common MRI perfusion techniques.
  • To guide the selection of appropriate MRI perfusion methods for diverse clinical applications.

Main Methods:

  • Discussion of established and emerging MRI perfusion methodologies.
  • Analysis of technique performance and clinical utility.

Main Results:

  • Overview of the principles behind different MRI perfusion techniques.
  • Summary of optimal techniques for specific clinical indications.

Conclusions:

  • The choice of MRI perfusion technique depends on the clinical question and patient.
  • A comprehensive understanding of available methods aids in effective clinical decision-making.