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An oxidopyrylium cyclization/ring-opening route to polysubstituted α-hydroxytropolones

Christine Meck1, Noushad Mohd, Ryan P Murelli

  • 1Department of Chemistry, Brooklyn College, The City University of New York, Brooklyn, New York 11210, USA.

Organic Letters
|November 22, 2012
PubMed
Summary

Synthesizing alpha-hydroxytropolones, which show therapeutic promise, is now more accessible. A new BCl(3)-mediated process and improved cycloaddition methods enable efficient production of these valuable compounds.

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