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Minocycline-induced hyperpigmentation in multibacillary leprosy.

Stephanie W Hu1, Maria R Robinson, Tracey Newlove

  • 1Department of Dermatology, New York University, New York, NY 10016, USA. stephwhu@gmail.com

The American Journal of Dermatopathology
|November 22, 2012
PubMed
Summary

Minocycline-induced hyperpigmentation in leprosy patients may present with new patterns. This study suggests additional subtypes of this adverse effect beyond the classic three clinical types.

Area of Science:

  • Dermatology
  • Pharmacology
  • Infectious Diseases

Background:

  • Minocycline is effective against Mycobacterium leprae, the causative agent of leprosy.

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  • Hyperpigmentation is a known adverse effect of minocycline therapy.
  • Classic minocycline-induced hyperpigmentation is categorized into three clinical and histological patterns.