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Updated: May 16, 2026

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
Published on: June 12, 2021
Tumor-infiltrating B cells: The ignored players in tumor immunology
Michael Linnebacher1, Claudia Maletzki
1Division of Molecular Oncology and Immunotherapy; Department of General Surgery; University of Rostock; Rostock, Germany.
Abstract:
B cells infiltrating into solid tumors are poorly investigated despite their described positive prognostic value. Whether this antitumor potential comes from either the antigen presentation or the antibody production capacity of B cells, or both, is unknown. Our recently published method on tumor-infiltrating B lymphocyte cloning may prove helpful in unraveling the actual relevance of these cells for tumor development and response to therapy.
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