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Updated: May 16, 2026

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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Opposing effects of androgen ablation on immune function in prostate cancer
1Molecular Pathology Graduate Program; Wake Forest School of Medicine; Winston Salem, NC USA.
Oncoimmunology
|November 22, 2012
Abstract:
Although it is recognized that immune function is modulated by androgen ablation therapy for prostate cancer, the long-term consequences are not completely understood. We recently showed that both effector and inhibitory immune mechanisms are amplified by androgen ablation, providing one explanation for only transient increases in immune function after castration.
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