Related Experiment Video
Updated: May 16, 2026

Optimizing Mouse Urodynamic Techniques for Improved Accuracy
Published on: June 7, 2024
A new technique for fast and safe collection of urine in newborns
María Luisa Herreros Fernández1, Noelia González Merino, Alfredo Tagarro García
1Pediatrics Department, University Infanta Sofía Hospital, San Sebastián de Los Reyes, Madrid, Spain. marisaherrerosfernandez@gmail.com
Aim:
To describe and test a new technique to obtain midstream urine samples in newborns.
Design And Methods:
This was a prospective feasibility and safety study conducted in the neonatal unit of University Infanta Sofía Hospital, Madrid. A new technique based on bladder and lumbar stimulation manoeuvres was tested over a period of 4 months in 80 admitted patients aged less than 30 days. The main variable was the success rate in obtaining a midstream urine sample within 5 min. Secondary variables were time to obtain the sample and complications.
Results:
This technique was successful in 86.3% of infants. Median time to sample collection was 45 s (IQR 30). No complications other than controlled crying were observed.
Conclusions:
A new, quick and safe technique with a high success rate is described, whereby the discomfort and waste of time usually associated with bag collection methods can be avoided.
Related Concept Videos
Filtration and Urine Formation
Formation of Concentrated Urine
Formation of Dilute Urine
Filtrate Osmolarity in the PCT
Initially, as the filtrate passes through the proximal convoluted tubule (PCT), its...
