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Related Concept Videos

Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...

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Multimodal Study of Murine Cardiovascular Remodeling: Four-Dimensional Ultrasound and Mass Spectrometry Imaging
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Published on: January 10, 2025

Cardiovascular molecular imaging: new methodological strategies.

Maria Filomena Santarelli1, Vincenzo Positano, Luca Menichetti

  • 1CNR Institute of Clinical Physiology, CNR Research Area, Via Moruzzi 1, 56124 Pisa, Italy. santarel@ifc.cnr.it

Current Pharmaceutical Design
|November 24, 2012
PubMed
Summary

Molecular imaging advances offer insights into cardiovascular disease but clinical use lags. Hyperpolarized (13)C magnetic resonance shows promise for monitoring heart energetics in preclinical studies.

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MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

Area of Science:

  • Cardiovascular Imaging
  • Molecular Imaging
  • Biomedical Engineering

Background:

  • Recent technical progress in small animal molecular imaging and specific probes.
  • Slow clinical translation of molecular imaging despite animal study successes.
  • Growing use of multimodality imaging in preclinical cardiovascular research.

Purpose of the Study:

  • To review preclinical cardiovascular applications of molecular imaging.
  • To discuss the potential clinical translation of advanced imaging techniques.
  • To highlight novel imaging probes and hyperpolarized magnetic resonance spectroscopy.

Main Methods:

  • Review of multimodality molecular imaging techniques in animal models.
  • Analysis of new multi-imaging probes, including PET/MRI probes.
  • Evaluation of hyperpolarized (13)C magnetic resonance spectroscopy for myocardial energetics.

Main Results:

  • Hybrid scanners enhance insights into cardiovascular disease pathophysiology in animals.
  • PET/MRI probes show effectiveness in hybrid scanner settings.
  • Hyperpolarized (13)C magnetic resonance demonstrates potential for monitoring myocardial energetics.

Conclusions:

  • Despite technical advances, clinical molecular imaging adoption is slow.
  • Multimodality imaging and novel probes are advancing preclinical cardiovascular research.
  • Hyperpolarized (13)C MRI is a promising technique for preclinical myocardial energetics assessment with potential for clinical translation.