Related Experiment Video
Updated: May 16, 2026

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs)
Published on: March 2, 2018
Challenging the use of adult neuropsychological models for explaining neurodevelopmental disorders: developed versus
1Centre for Brain & Cognitive Development, Birkbeck, University of London, London, UK. a.karmiloff-smith@bbk.ac.uk
Abstract:
In this paper, I contrast approaches from adult neuropsychology that seek selective, domain-specific deficits with approaches aimed at understanding the dynamics of developmental trajectories in children with genetic disorders. I stress the crucial difference between developed brains damaged in their mature state, and atypically developing brains. I also challenge the search for single genes to explain selective cognitive-level outcomes. Throughout, the paper argues that it is critical to trace cognitive-level deficits back to their basic-level processes in infancy, where genes are likely to exert their early influences, if we are to understand both the impairments and proficiencies displayed in children with neurodevelopmental disorders.
Related Concept Videos
Revisionist Views of Adolescent and Adult Cognition
Information Processing Approach
Introduction to Developmental Psychology
Three Developmental Domains
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...
Theoretical Approaches to Psychological Disorder
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
The Nativist Approach
