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Updated: May 16, 2026
07:27
Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
One heart in 3 patients
Mislav Planinc1, Tomislav Mihaljevic, Craig M Jarrett
1Heart and Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
The Annals of Thoracic Surgery
|November 27, 2012
Summary
This case report details the successful reuse of a transplanted heart in a patient with amyloid cardiomyopathy. Despite developing leukemia, the heart transplant offered a viable option amid donor organ scarcity.
Area of Science:
- Cardiology
- Transplantation Medicine
- Oncology
Background:
- Amyloid-induced cardiomyopathy presents a significant challenge in end-stage heart failure.
- Heart transplantation is a critical treatment option for eligible patients.
- Donor organ shortage necessitates exploring innovative strategies like organ reuse.
Observation:
- A 63-year-old male, a second heart transplant recipient, had end-stage heart failure due to amyloid cardiomyopathy.
- The patient experienced an uneventful post-transplant recovery initially.
- Six months post-transplantation, the patient was diagnosed with acute myelogenous leukemia.
Findings:
- The patient's death, 10 months after transplantation, was attributed to malignancy in an immunosuppressed state.
- This case highlights the complex interplay between immunosuppression, malignancy, and organ transplant outcomes.
- The transplanted heart's function was maintained despite the patient's subsequent illness.
Implications:
- Successful reuse of a transplanted heart is feasible even in complex clinical scenarios.
- Careful patient selection is paramount for successful heart transplant reuse.
- This approach offers a potential solution to the critical shortage of donor organs for heart transplantation.
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