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[Febrile urinary tract infection in infants: diagnostic strategy]
1Université Lille Nord-de-France, UDSL, CHRU Lille, Urgences pédiatriques et maladies infectieuses et EA2694, Sante publique: épidémiologie et qualité des soins, 2, avenue Oscar Lambret, 59000 Lille, France. francois.dubos@chru-lille.fr
Insights
Diagnosing febrile urinary tract infections (UTIs) in young children is challenging. This review highlights clinical signs, urine collection methods, and rapid tests to improve accurate UTI diagnosis in children under two.
Area of Science:
- Pediatrics
- Infectious Diseases
- Diagnostic Medicine
Context:
- Febrile urinary tract infections (UTIs) are common in young children, with prevalence varying by age and sex.
- Accurate diagnosis is complicated by a lack of specific clinical signs beyond high fever.
- Current diagnostic approaches require optimization to reduce contamination and improve accuracy.
Purpose:
- To review the diagnostic utility of clinical signs and patient history in identifying UTIs in children under two.
- To evaluate optimal urine collection techniques for pediatric patients.
- To assess the performance of rapid diagnostic tests in confirming or excluding acute UTIs.
Summary:
- Fever >39°C for 48h is the primary indicator, but other clinical or historical data offer limited diagnostic value for pediatric UTIs.
- Appropriate urine collection methods are crucial to prevent contamination and ensure reliable results.
- Rapid diagnostic tests, including dipstick urinalysis and microscopy, can aid in increasing or decreasing the probability of UTI.
Impact:
- Improved diagnostic strategies for febrile UTIs in infants and young children.
- Reduced misdiagnosis and delayed treatment of pediatric UTIs.
- Enhanced clinical decision-making through better understanding of diagnostic test performance.
Abstract:
The diagnosis of febrile urinary tract infection in young children is difficult. Its prevalence is about 7.5 % but varies from 2 to 20 % according to the sex and age of the child. Except fever higher than 39°C for at least 48 h, no other anamnestic signs or from the clinical examination change significantly the probability of having a urinary tract infection or not. The most appropriate method of urine collection should be proposed to children clinically suspected of urinary tract infection, to avoid contamination and allow a proper diagnosis. Rapid tests (such as dipstick tests and microscopy) are useful to improve the likelihood of the diagnosis. This review focuses on the usefulness of anamnestic signs and clinical data, the way to collect urine and the performance of rapid diagnostic tests to increase or decrease the likelihood of acute urinary tract infection in children less than two years of age.
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