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Related Concept Videos

Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...

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Related Experiment Video

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Examination of Thymic Positive and Negative Selection by Flow Cytometry
14:29

Examination of Thymic Positive and Negative Selection by Flow Cytometry

Published on: October 8, 2012

The immunologic self.

S A Hoffman1

  • 1Human Dimensions of Biology, Neuroimmunology Laboratory, School of Life Sciences, Arizona State University, Tempe, AZ 85287-4501, USA. SteveHoffman@asu.edu

Perspectives in Biology and Medicine
|November 27, 2012
PubMed
Summary
This summary is machine-generated.

This study explores the concept of "self" through immunology, proposing that immunological and psychological aspects are interconnected facets of a unified self. It challenges simplistic, internal views of personal identity.

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Last Updated: May 16, 2026

Examination of Thymic Positive and Negative Selection by Flow Cytometry
14:29

Examination of Thymic Positive and Negative Selection by Flow Cytometry

Published on: October 8, 2012

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions
05:58

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Published on: April 20, 2016

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11:12

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Area of Science:

  • Immunology
  • Philosophy of Mind
  • Psychology

Background:

  • The concept of
  • self
  • lacks a satisfactory definition, with diverse historical characterizations.
  • Immunology, the study of self/non-self discrimination, offers a novel perspective on personal identity.
  • Existing definitions often focus narrowly on the body, brain, or consciousness.

Purpose of the Study:

  • To examine the concept of self from an immunological viewpoint.
  • To integrate immunological and psychological perspectives on the self.
  • To propose criteria for a comprehensive conceptualization of personal identity.

Main Methods:

  • Philosophical analysis of the concept of self.
  • Exploration of immunological principles related to self-recognition.
  • Integration of findings from immunology and psychology.

Main Results:

  • The immunological self and the psychological self are proposed as two aspects of a single, unified self.
  • Criteria for an adequate conceptualization of the self are offered.
  • The study highlights the limitations of purely mentalistic or inward-focused self-concepts.

Conclusions:

  • A unified conception of self requires integrating both immunological and psychological dimensions.
  • Moving beyond simplistic, internal definitions is crucial for understanding personal identity.
  • The immunological perspective provides valuable insights into the philosophical nature of the self.