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The treatment of systemic lupus proliferative nephritis

Marilynn G Punaro1

  • 1UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9063, USA, Marilynn.Punaro@UTSouthwestern.edu.

Pediatric Nephrology (Berlin, Germany)
|November 27, 2012
PubMed

Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE) in childhood affecting more than 80% of patients. Treatment of this complication has undergone significant evolution in recent years. A series of randomized controlled trials has clarified the role of a variety of immunomodulating regimens including some novel biologic medications. This review touches on the major trials that have influenced practice and shaped current thinking about the treatment of proliferative lupus glomerulonephritis.

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