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An Electroporation Method to Transform Rickettsia spp. with a Fluorescent Protein-Expressing Shuttle Vector in Tick Cell Lines

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Rickets: Part II.

Richard M Shore¹, Russell W Chesney

¹Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Box 9, 225 E. Chicago Ave., Chicago, IL 60611, USA. rshore@northwestern.edu

Pediatric Radiology

|November 27, 2012

Summary

This summary is machine-generated.

This review details vitamin D deficiency rickets, covering its causes, symptoms, and imaging. It also explores other rickets types and infant fracture links.

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Area of Science:

Pediatrics
Endocrinology
Radiology

Background:

Rickets is a bone disease affecting children, primarily caused by vitamin D deficiency.
This review continues a two-part series on rickets, focusing on specific diagnostic and clinical aspects.

Purpose of the Study:

To detail the pathophysiology, clinical presentation, pathoanatomy, and radiographic findings of vitamin D deficiency rickets.
To discuss differential diagnoses for rickets and the association between vitamin D metabolites and infant fractures.

Main Methods:

Literature review and synthesis of existing research on rickets.
Analysis of clinical features, pathoanatomic changes, and radiographic evidence.

Main Results:

Vitamin D deficiency rickets presents with characteristic clinical and radiographic findings.
Differential diagnosis is crucial, and low vitamin D metabolites may be linked to infant fractures.

Conclusions:

Understanding the nuances of vitamin D deficiency rickets is essential for accurate diagnosis and management.
Further research is warranted to clarify the relationship between vitamin D and unexplained infant fractures.