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Updated: May 16, 2026

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles
Published on: November 1, 2012
Effect of the rest interval duration between contractions on muscle fatigue
Daniel V Nogueira1, Sidney B Silva, Luiz Carlos de Abreu
1Universidade do Vale do Paraíba-UNIVAP/Grupo de Instrumentação e Processamento de Sinais-GIPSI, IP&D, Rua Tertuliano Delphim Jr, 181 São José dos Campos, São Paulo 12246-080, Brazil.
Background:
We aimed to investigate the effect of rest interval, between successive contractions, on muscular fatigue.
Methods:
Eighteen subjects performed elbow flexion and extension (30 repetitions) on an isokinetic dynamometer with 80º of range of motion. The flexion velocity was 120º/s, while for elbow extension we used 5 different velocities (30, 75, 120, 240, 360º/s), producing 5 different rest intervals (2.89, 1.28, 0.85, 0.57 and 0.54 s).
Results:
We observed that when the rest interval was 2.89 s there was a reduction in fatigue. On the other hand, when the rest interval was 0.54 s the fatigue was increased.
Conclusions:
When the resting time was lower (0.54 s) the decline of work in the flexor muscle group was higher compared with different rest interval duration.
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