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Updated: May 16, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

[Important genodermatoses for the practitioner].

P Itin¹, D A Salgado

¹Dermatologie Universitätsspital Basel, Petersgraben 4, 4031, Basel, Schweiz. peter.itin@unibas.ch

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete

|November 28, 2012

Summary

This summary is machine-generated.

Genetic skin diseases (genodermatoses) are influenced by genetics and environment. Porokeratoses, ichthyoses, Darier disease, neurofibromatosis, and epidermolysis bullosa are the most common genodermatoses in hospital dermatology.

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Last Updated: May 16, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

Genetics and molecular biology
Dermatology
Epidemiology

Context:

Monogenic diseases result from single gene mutations, with over 10,000 identified by WHO.
Molecular genetic testing is available for approximately 1,000 monogenic diseases.
Genodermatoses are a well-characterized group of genetic skin disorders, with OMIM serving as a key diagnostic database.

Purpose:

To present epidemiologic data on genodermatoses encountered in a hospital-based dermatology department.
To identify the most prevalent genodermatoses in clinical practice.

Summary:

This study analyzed the frequency of various genodermatoses at the Department of Dermatology, University Hospital Basel.
The most common genodermatoses observed were porokeratoses, ichthyoses, Darier disease, neurofibromatosis, and epidermolysis bullosa.
These five conditions constitute 91% of all genodermatoses managed in the department.

Impact:

Provides insights into the clinical epidemiology of genodermatoses in a tertiary care setting.
Highlights the significant burden of specific genetic skin diseases in daily dermatological practice.
Informs diagnostic and management strategies for common genodermatoses.