Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Characteristics and Nomenclature of Copolymers01:24

Characteristics and Nomenclature of Copolymers

Copolymers are the products obtained from the polymerization of multiple monomer species. So, in a polymer chain itself, there can be multiple repeating units that come from different monomers. The process of synthesizing a polymer from different monomer species is called copolymerization. When two monomers are involved, the polymer is known as a bipolymer. Polymers with three and four monomers are termed terpolymers and quaterpolymers, respectively. Figure 1 depicts the copolymerization of...
Fibril-associated Collagen01:11

Fibril-associated Collagen

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
Complexation Equilibria: The Chelate Effect01:19

Complexation Equilibria: The Chelate Effect

In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neural correlates and network dynamics of uncommon semiologies in the cingulo-insulo-opercular network explored with Stereo-EEG.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

'No-No' head movement as a true epileptic phenomenon - A case series with SEEG and signal processing evaluation.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Inorganic Antimicrobial Materials.

ACS nano·2026
Same author

Pluripotent stem cell-derived extracellular vesicles: Cell type-dependent effect on tumorigenicity in cancer cell lines.

Journal of cell communication and signaling·2026
Same author

Layered structuring of nutritional components in meat analogues by rolling droplet-interfacial polyelectrolyte complexation (RD-IPC).

Food research international (Ottawa, Ont.)·2026
Same author

"Who 'nose' when a seizure will happen?" Prodromal olfactory loss as a first clinical indicator of seizure activity in temporal lobe epilepsy.

Epileptic disorders : international epilepsy journal with videotape·2025

Related Experiment Video

Updated: May 16, 2026

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
11:13

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules

Published on: August 19, 2015

Multicomponent fibers by multi-interfacial polyelectrolyte complexation.

Andrew C A Wan1, Meng Fatt Leong, Jerry K C Toh

  • 1Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore. awan@ibn.a-star.edu.sg

Advanced Healthcare Materials
|November 28, 2012
PubMed
Summary
This summary is machine-generated.

Multi-interfacial polyelectrolyte complexation (MIPC) creates patterned multicomponent fibers. Encapsulated cells show pattern-dependent migration, aggregation, and spreading within these novel biomaterials.

More Related Videos

Assembly and Characterization of Polyelectrolyte Complex Micelles
08:44

Assembly and Characterization of Polyelectrolyte Complex Micelles

Published on: March 2, 2020

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

Related Experiment Videos

Last Updated: May 16, 2026

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
11:13

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules

Published on: August 19, 2015

Assembly and Characterization of Polyelectrolyte Complex Micelles
08:44

Assembly and Characterization of Polyelectrolyte Complex Micelles

Published on: March 2, 2020

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

Area of Science:

  • Materials Science
  • Biomaterials Engineering
  • Cell Biology

Background:

  • Polyelectrolyte complexation is a versatile method for fabricating materials.
  • Controlling fiber architecture is crucial for biomaterial applications.
  • Multi-interfacial approaches offer new possibilities for complex material design.

Purpose of the Study:

  • To investigate the fabrication of patterned multicomponent fibers using multi-interfacial polyelectrolyte complexation (MIPC).
  • To explore the cellular response to fibers created through MIPC with varying numbers of interfaces.
  • To establish a link between initial cell/matrix patterns and subsequent cell behavior within the fibers.

Main Methods:

  • Utilized multi-interfacial polyelectrolyte complexation (MIPC) with 2, 3, and 4 polyelectrolyte complex interfaces.
  • Fabricated various patterned multicomponent fibers by drawing from fused nascent fibers.
  • Encapsulated cells within the MIPC-derived fibers and observed their behavior.

Main Results:

  • Successfully generated diverse patterned multicomponent fibers via MIPC.
  • Demonstrated that the number of interfaces influences fiber pattern complexity.
  • Observed distinct cell migration, aggregation, and spreading behaviors correlated with the initial cell or matrix patterns within the fibers.

Conclusions:

  • MIPC is an effective technique for creating complex, patterned multicomponent fibers.
  • The resulting fiber architecture influences encapsulated cell behavior.
  • This technology holds potential for developing advanced biomaterials with controlled cellular responses.