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Updated: May 16, 2026

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
Published on: August 19, 2015
Multicomponent fibers by multi-interfacial polyelectrolyte complexation
Andrew C A Wan1, Meng Fatt Leong, Jerry K C Toh
1Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore. awan@ibn.a-star.edu.sg
Abstract:
In multi-interfacial polyelectrolyte complexation (MIPC), fusion of nascent fibers from multiple interfaces brings the interfaces to a point from which a composite fiber is drawn. MIPC applied to two, three, and four polyelectrolyte complex interfaces leads to various patterned multicomponent fibers. Cells encapsulated in these fibers exhibit migration, aggregation and spreading in relation to the initial cell or matrix pattern.
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