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Preparation of Functional Silica Using a Bioinspired Method
Published on: August 1, 2018
Enhanced enzymatic thermal stability and activity in functionalized mesoporous silica monitored by (31) p NMR
Kheireddine El-Boubbou1, David A Schofield, Christopher C Landry
1Department of Chemistry, University of Vermont, 82 University Place, Burlington, VT 05405, USA.
Advanced Healthcare Materials
|November 28, 2012
Abstract:
Organophosphorus hydrolase (OPH) is immobilized on ammonium-modified mesoporous silica particles. Thermal stability and activity are measured with a (31) P NMR assay of the conversion of paraoxon (toxic) to its non-toxic hydrolysis product. After immobilization, OPH is significantly more active at room temperature and retained activity even after being heated to 45 °C for 1 month.
