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Updated: May 16, 2026

Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts
Published on: May 25, 2018
Basosquamous cell carcinoma developing from a renal transplantation recipient
Akira Tsukada1, Taku Fujimura, Sadanori Furudate
1Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Abstract:
We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs.
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