Related Experiment Videos
Punctate Porokeratosis Presenting as Multiple Hyperkeratotic Papules on the Bilateral Hands: A Case Report
Xiaojing Bu1, Siyuan Yao1, Ling Huang1
1Department of Dermatology, The First Affiliated Hospital of Dali University, Dali, China.
Introduction:
Punctate porokeratosis (PK) is a rare variant of PK characterized by small, keratotic papules on the palms and soles. It may occur in adolescence or early adulthood, and it is diagnosed mainly based on the histopathological findings of a cornoid lamella. In this report, we described a case with atypically larger papules and distinct dermoscopic features.
Case Presentation:
A 36-year-old woman presented with a 1-year history of asymptomatic hyperkeratotic papules on both hands. Physical examination showed multiple, discrete, translucent, hyperkeratotic papules measuring 2-8 mm in diameter (larger than the classic papules of 1-2 mm in diameter) on the palms and fingers. Dermoscopic examination revealed a light red background with yellowish-white scales and irregular vascular structures, whereas the typical "double-track" sign was absent.
Conclusion:
Histopathological examination is essential for diagnosing punctate PK, particularly in cases where lesions are unusually large or dermoscopic presentations are atypical.
Related Concept Videos
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...