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Related Concept Videos

The Spinal Cord01:54

The Spinal Cord

The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Spinal Cord01:26

Spinal Cord

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Spinal Cord: Information Processing01:10

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Sensory Information Processing
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Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...

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In Vivo Mouse Model of Spinal Implant Infection
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Published on: June 23, 2020

Spinal cord infections.

Megan B Richie1, Amy A Pruitt

  • 1Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA.

Neurologic Clinics
|November 29, 2012
PubMed
Summary
This summary is machine-generated.

Spinal cord infections require prompt diagnosis and treatment. This guide details a clinical approach using risk factors and symptoms to identify and manage these urgent central nervous system (CNS) infections.

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Diagnostic Imaging

Background:

  • Spinal cord infections present significant diagnostic and management challenges.
  • Early identification is crucial for effective treatment and patient outcomes.
  • Vulnerable populations, including immunocompromised individuals and travelers, are at increased risk.

Purpose of the Study:

  • To outline a systematic clinical approach for diagnosing potential spinal cord infections.
  • To discuss the spectrum of spinal cord infections in high-risk patient groups.
  • To review diagnostic investigations and initial management strategies.

Main Methods:

  • Clinical assessment based on demographic risk factors and central nervous system (CNS) and extra-CNS signs.
  • Review of serologic and cerebrospinal fluid (CSF) investigations for various pathogens (bacterial, viral, parasitic).
  • Correlation of findings with characteristic magnetic resonance imaging (MRI) and other imaging modalities.

Main Results:

  • Detailed discussion of clinical presentations and risk factors associated with spinal cord infections.
  • Outlined diagnostic workup including laboratory tests and neuroimaging.
  • Consideration of specific pathogens and their typical manifestations.

Conclusions:

  • A structured clinical approach, integrating risk factors, symptoms, and diagnostic tests, is essential for managing spinal cord infections.
  • Understanding the diverse spectrum of disease in at-risk populations aids in timely diagnosis.
  • Effective initial management strategies are critical for improving patient prognosis.