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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

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Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

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Related Experiment Videos

Cervical spondylotic myelopathy.

Michel Toledano1, J D Bartleson

  • 1Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

Neurologic Clinics
|November 29, 2012
PubMed
Summary

Cervical spondylotic myelopathy (CSM) is a common cause of myelopathy in older adults. This review covers CSM

Area of Science:

  • Neurology
  • Neurosurgery
  • Orthopedics

Background:

  • Cervical spondylotic myelopathy (CSM) is the most frequent cause of myelopathy in adults over 55.
  • The differential diagnosis for CSM is extensive, encompassing various conditions that can mimic or cause myelopathy.

Purpose of the Study:

  • To provide a comprehensive overview of cervical spondylotic myelopathy (CSM).
  • To summarize the pathophysiology, clinical presentation, differential diagnosis, diagnostic evaluation, and natural history of CSM.
  • To review available treatment options and their associated complications.

Main Methods:

  • Literature review and synthesis of existing research on CSM.
  • Analysis of clinical presentations, diagnostic criteria, and treatment outcomes for CSM.

Related Experiment Videos

Main Results:

  • CSM presents a broad differential diagnosis, requiring careful evaluation.
  • Understanding the pathophysiology and natural history is crucial for diagnosis and management.
  • Various treatment options exist, each with potential complications.

Conclusions:

  • CSM is a significant neurological condition in the aging population.
  • Accurate diagnosis and appropriate management are essential for patient outcomes.
  • Further research may refine treatment strategies and reduce complications.