Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the posterior columns...
Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
Sensory Perception: Organization of the Somatosensory System01:11

Sensory Perception: Organization of the Somatosensory System

The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
Desensitization and Tachyphylaxis01:20

Desensitization and Tachyphylaxis

Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
Several...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Listening to the Body: Interoceptive Awareness and Eating Disorder Vulnerability in Adolescents with Inflammatory Bowel Diseases.

Children (Basel, Switzerland)·2026
Same author

Interoception in Female Adolescents with Inflammatory Bowel Diseases <i>Versus</i> Restrictive Eating Disorders.

Nutrients·2026
Same author

Interoception, Self-Injury and Suicidal Ideation in Female Adolescents With Restrictive Eating Disorders and Co-Morbid Borderline Personality Disorder.

Clinical psychology & psychotherapy·2025
Same author

A Critical Examination of the Clinical Diagnosis of Functional Tic-like Behaviors.

Movement disorders clinical practice·2024
Same author

Functional Tic-like Behaviors: From the COVID-19 Pandemic to the Post-Pandemic Era.

Healthcare (Basel, Switzerland)·2024
Same author

Outcomes of Percutaneous Endoscopic Gastrostomy in Huntington's Disease at a Tertiary Center.

Movement disorders clinical practice·2024

Related Experiment Video

Updated: May 16, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
07:38

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats

Published on: May 27, 2021

Premonitory urges and sensorimotor processing in Tourette syndrome.

Sangeerthana Rajagopal1, Stefano Seri And, Andrea Eugenio Cavanna

  • 1The Michael Trimble Neuropsychiatry Research Group, Department of Neuropsychiatry, BSMHFT and University of Birmingham, Birmingham, UK.

Behavioural Neurology
|November 29, 2012
PubMed
Summary

Patients with Tourette syndrome experience premonitory urges before tics. This review suggests alterations in brain sensorimotor processing may underlie these urges, offering potential new treatment targets.

More Related Videos

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
11:17

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Published on: November 25, 2025

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Na&#239;ve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Related Experiment Videos

Last Updated: May 16, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
07:38

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats

Published on: May 27, 2021

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
11:17

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Published on: November 25, 2025

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Na&#239;ve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Area of Science:

  • Neuroscience
  • Clinical Neurology
  • Psychiatry

Background:

  • Tourette syndrome (TS) is characterized by motor and vocal tics.
  • Premonitory urges, or sensory experiences preceding tics, are central to TS phenomenology.
  • The neural underpinnings of these urges remain largely unknown.

Purpose of the Study:

  • To systematically review published literature on the pathophysiological mechanisms of premonitory urges in Tourette syndrome.
  • To consolidate current understanding of the brain processes associated with premonitory urges.

Main Methods:

  • Systematic literature review of peer-reviewed studies.
  • Analysis of research investigating sensory processing and sensorimotor pathways in Tourette syndrome.

Main Results:

  • Preliminary evidence suggests alterations in sensorimotor processing at cortical and subcortical levels.
  • Specific brain regions and networks involved in sensory gating and motor control may be implicated.
  • The review highlights a need for further research into the neurobiology of premonitory urges.

Conclusions:

  • Understanding the brain correlates of premonitory urges is crucial for advancing Tourette syndrome research.
  • Identifying these neural targets could pave the way for novel therapeutic strategies.
  • Future research should focus on elucidating the precise mechanisms linking sensorimotor alterations to premonitory urges in TS.