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Updated: May 16, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
Published on: February 24, 2023
Combined targeted therapy and immunotherapy in the treatment of advanced melanoma
James S Wilmott1, Richard A Scolyer, Georgina V Long
1Melanoma Institute Australia; Sydney, NSW Australia ; University of Sydney; Sydney, NSW Australia.
Abstract:
Recently, a CTLA-4 antibody and BRAF inhibitors showed survival benefits in advance melanoma treatment. The documentation of immune infiltrates in melanomas early during BRAF inhibitor therapy provides a scientific rationale for combination therapy with both treatments with possible synergistic benefits. This commentary reviews immune responses induced by BRAF inhibitors.
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