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The influence of substitute materials on bone density after maxillary sinus augmentation: a microcomputed tomography
Sebastian Kühl1, Hermann Götz, Christoph Brochhausen
1School of Dental Medicine, Department of Oral Surgery, Oral Radiology and Oral Medicine, University of Basel, Basel, Switzerland. sebastian.kuehl@unibas.ch
The International Journal of Oral & Maxillofacial Implants
|November 29, 2012
Summary
Adding bone substitutes like beta-tricalcium phosphate (Β-TCP) and hydroxyapatite (HA) to particulated autogenous bone (PAB) for maxillary sinus augmentation increases bone density. Further research with larger sample sizes is recommended.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Medicine
- Biomaterials Science
Background:
- Maxillary sinus augmentation is a common procedure to increase bone volume for dental implant placement.
- Autogenous particulated bone (PAB) is a traditional grafting material.
- The use of bone substitute materials aims to enhance bone regeneration and graft consolidation.
Purpose of the Study:
- To investigate the effect of adding beta-tricalcium phosphate (Β-TCP) and hydroxyapatite (HA) to PAB on the density of grafted bone.
- To evaluate bone density changes after maxillary sinus augmentation using different graft compositions.
Main Methods:
- A randomized clinical study involving 30 patients undergoing lateral antrostomy.
- Grafting materials included PAB alone (control), PAB with Β-TCP, and PAB with Β-TCP and HA.
- Microcomputed tomography (Μ-CT) was used to analyze bone density of graft samples immediately after surgery and after 5 months.
Main Results:
- All groups demonstrated an increase in bone density after 5 months of healing.
- Statistical comparison between groups was not possible due to a high dropout rate and small sample size.
Conclusions:
- Bone density increases significantly after maxillary sinus augmentation with PAB, whether used alone or combined with HA and/or Β-TCP.
- Larger sample sizes and split-mouth designs are necessary to detect statistically significant differences between various graft materials.