Related Experiment Video
Updated: May 16, 2026

Preparation of Herbal Medicine: Er-Xian Decoction and Er-Xian-containing Serum for In Vivo and In Vitro Experiments
Published on: May 31, 2017
[Pharmacodynamics of water extracts from Atractylodes lancea before and after processing]
Yanju Liu1, Wenwen Chen, Min Zeng
1Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China. lyj1965954@sohu.com
Objective:
To study the pharmacological changes of Atractylodes lancea before and after processing and the processing mechanism on the basis of the pharmacological changes.
Method:
The model of dampness retention in the middle-jiao rats was established to determine small intestine peristalsis rate, GAS level, urine volume and AQP2 content from urine in different groups.
Result:
All treatment groups showed increase in small intestinal peristalsis rate and GAS level. The bran-processed group showed significant difference from the negative group. The high dose A. lancea group showed increase in urine volume and decrease in urine AQP2 content in model rats, which were different from the negative group.
Conclusion:
Water extracts from bran-processed A. lancea can obviously increase small intestinal peristalsis and GAS level, indicating that A. lancea has the effect for strengthening spleen and stomach after stir-baking with bran. Its impact on urine and urine AQP2 content in model rats demonstrates that its dryness of A. lancea is alleviated after stir-baking with bran.
Related Concept Videos
Factors Influencing Drug Absorption: Pharmaceutical Parameters
Pharmacodynamic Responses: Different Types
Pharmacokinetics: Overview
Bioavailability Enhancement: Drug Permeability Enhancement
