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Updated: May 16, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

[Squamous cell carcinoma--case report].

Sanja Poduje¹, Dubravko Huljev, Zeljkica Cubrilović

¹Sestre milosrdnice University Hospital Center, University Department of Dermatovenereology Zagreb, Croatia. sanja.poduje@kbcsm.hr

Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti

|December 1, 2012

Summary

This summary is machine-generated.

Marjolin's ulcer, a rare skin cancer developing in chronic wounds, can metastasize. Early biopsy of non-healing ulcers is crucial for timely diagnosis and treatment of squamous cell carcinoma.

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Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

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Last Updated: May 16, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

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Published on: August 9, 2024

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Published on: May 11, 2016

Area of Science:

Dermatology
Oncology
Pathology

Background:

Marjolin's ulcer is a malignancy arising in chronic wounds, scars, or fistulas.
It predominantly presents as squamous cell carcinoma, accounting for 2-5% of all cutaneous squamous cell carcinomas.

Observation:

A 60-year-old male presented with a 15-year-old chronic ulcer on his right leg, initially misdiagnosed as a venous ulcer.
Sudden ulcer enlargement prompted a biopsy, confirming invasive squamous cell carcinoma.
Imaging revealed metastatic squamous cell carcinoma in the inguinal lymph node.

Findings:

The patient underwent tumor excision and lymph node dissection.
Tumor relapse occurred in the skin and lymph node, necessitating ongoing oncological and surgical supervision.

Implications:

This case underscores the importance of biopsies for non-healing ulcers, especially when typical risk factors are absent.
Prompt diagnosis and biopsy can prevent delayed treatment and reduce complications associated with Marjolin's ulcer.