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Updated: May 16, 2026

Discovery of New Intracellular Pathogens by Amoebal Coculture and Amoebal Enrichment Approaches
Published on: October 27, 2013
Symbiotic interactions between free-living amoeba and harboured mercury-resistant bacteria
1Laboratoire d'Hydrobiologie de l'Environnement, Faculté de Pharmacie de Strasbourg, Illkirch, France.
Abstract:
A co-culture of environmental Acanthamoeba sp. associated to Hg-sensitive, narrow or broad-spectrum Hg-resistant Aeromonas sp. strains was exposed to HgCl(2) and phenylmercuric acetate. Amoebic growth depended on the Hg-resistance determinants of harboured bacteria. This laboratory model helped in understanding the mechanisms of Hg-resistance observed in amoeba isolated in river waters after a mercuric pollution. Amoeba acquired Hg-resistance by using symbiotic resistant bacteria.
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