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Related Concept Videos

Preparation and Reactions of Sulfides02:26

Preparation and Reactions of Sulfides

Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
Microbes and the Sulfur Cycle01:29

Microbes and the Sulfur Cycle

Sulfur is a vital element in Earth's biogeochemical systems. It transitions through various inorganic states, including sulfate (SO₄²⁻), elemental sulfur (S⁰), and sulfide (S²⁻). Abiotic and biological mechanisms across oxic and anoxic environments intricately mediate these transformations. Sulfate, the most oxidized form of sulfur, is predominantly stored in rocks, marine sediments, and oceanic waters, acting as a long-term reservoir in the global sulfur cycle.In oxic environments,...
Preparation and Reactions of Thiols02:33

Preparation and Reactions of Thiols

Thiols are prepared using the hydrosulfide anion as a nucleophile in a nucleophilic substitution reaction with alkyl halides. For instance, bromobutane reacts with sodium hydrosulfide to give butanethiol.

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Related Experiment Video

Updated: May 16, 2026

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
03:55

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria

Published on: June 27, 2022

Hydrogen sulfide as an oxygen sensor.

Kenneth R Olson1

  • 1Indiana University School of Medicine, South Bend, South Bend, IN 46617, USA. kolson@nd.edu

Clinical Chemistry and Laboratory Medicine
|December 1, 2012
PubMed
Summary
This summary is machine-generated.

Hydrogen sulfide (H2S) metabolism acts as an oxygen (O2) sensor in vertebrates. Its production and oxidation balance O2 levels, influencing physiological responses to hypoxia.

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Measurement of H2S in Crude Oil and Crude Oil Headspace Using Multidimensional Gas Chromatography, Deans Switching and Sulfur-selective Detection
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Measurement of H2S in Crude Oil and Crude Oil Headspace Using Multidimensional Gas Chromatography, Deans Switching and Sulfur-selective Detection

Published on: December 10, 2015

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Last Updated: May 16, 2026

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
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Measurement of H2S in Crude Oil and Crude Oil Headspace Using Multidimensional Gas Chromatography, Deans Switching and Sulfur-selective Detection
08:37

Measurement of H2S in Crude Oil and Crude Oil Headspace Using Multidimensional Gas Chromatography, Deans Switching and Sulfur-selective Detection

Published on: December 10, 2015

Area of Science:

  • Physiology
  • Biochemistry
  • Cell Biology

Background:

  • Oxygen (O2) monitoring is vital for animal survival.
  • Vertebrates utilize O2-sensing cells for homeostasis.
  • Mechanisms of O2 sensing transduction remain unclear.

Purpose of the Study:

  • To propose and elaborate on hydrogen sulfide (H2S) metabolism as an O2 sensor.
  • To explain the H2S-mediated O2 sensing mechanism.

Main Methods:

  • Review of experimental observations in O2-sensing tissues.
  • Analysis of the relationship between H2S metabolism and O2 levels.
  • Examination of evolutionary links between H2S and O2.

Main Results:

  • Exogenous H2S mimics hypoxic physiological responses.
  • Cellular H2S production inversely correlates with partial pressure of O2 (pO2).
  • H2S biosynthesis modulators affect hypoxic responses; H2S and hypoxia share effector pathways.

Conclusions:

  • H2S metabolism is a viable O2 sensing mechanism.
  • H2S concentration is regulated by production-oxidation balance.
  • The H2S-O2 relationship has deep evolutionary roots.