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Published on: July 22, 2017
Spinal cord infarction with cervical angina
Yoshiharu Nakae1, Ken Johkura, Yosuke Kudo
1Department of Neurology, Hiratsuka Kyosai Hospital, Hiratsuka, Japan. nakae-y@kkr.hiratsuka.kanagawa.jp
Insights
Cervical angina, chest pain from cervical spine issues, can be caused by spinal cord infarction. This rare condition may affect the sympathetic nervous system, leading to symptoms like bradycardia.
Area of Science:
- Neurology
- Cardiology
- Spinal Cord Medicine
Background:
- Cervical angina is chest pain mimicking cardiac angina, originating from cervical spine disorders, often cervical spondylosis.
- The sympathetic nervous system plays a role in cardiovascular regulation, with fibers originating from cervical and thoracic spinal cord segments.
Observation:
- A 66-year-old man experienced chest pain and bilateral arm palsy.
- Neurological exam revealed C7-T1 level deficits; MRI showed a spinal cord lesion, diagnosed as spinal cord infarction.
- Severe sinus bradycardia was noted, improving over 5 weeks.
Findings:
- Spinal cord infarction can disrupt sympathetic control, leading to bradycardia, particularly with cervical or high-thoracic lesions.
- The patient's bradycardia suggested sympathetic system impairment at cervical and thoracic levels.
- Cervical angina in this case was mediated via the sympathetic nervous system.
Implications:
- This case highlights spinal cord infarction as a rare cause of cervical angina.
- Understanding the neurological basis of cervical angina is crucial for accurate diagnosis and management.
- Further research into the neuro-cardiac axis in spinal cord injuries is warranted.
Abstract:
Cervical angina is defined as chest pain resembling true cardiac angina but originating from disorders of the cervical spine. Cervical angina is caused by cervical spondylosis in most cases. A 66-year-old man presented with bilateral arm palsy after chest pain resembling angina pectoris. Neurological examination revealed motor and sensory disturbances of the C7 to T1 level, and magnetic resonance imaging showed a hyperintense spinal cord lesion on T2-weighted imaging. Spinal cord infarction was diagnosed. Severe sinus bradycardia was identified on admission, and improved over the course of 5 weeks. Sympathetic afferent fibers from the heart and coronary arteries generally have their cell bodies in the dorsal root ganglia of the C8 to T9 spinal segments. Electrical stimulation of cardiopulmonary afferent fibers excites spinothalamic tract cells in the T1 to T6 segments of the spinal cord. Spinal cord injury can result in the loss of supraspinal control of the sympathetic system and can cause bradycardia, as commonly seen in patients with severe lesions of the cervical or high-thoracic (T6 or above) spinal cord. Bradycardia in the present case suggested impairment of the sympathetic system at the cervical and thoracic levels. These findings indicated that cervical angina in this case was mediated through the sympathetic nervous system. This represents only the second report of cervical angina caused by spinal cord infarction.
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