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Maxillary stability after Le Fort I osteotomy with self-setting α-tricalcium phosphate and an absorbable plate
1Department of Oral and Maxillofacial Surgery, Division of Medicine, Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi, 1110 Shimokato, Chuo-shi,Yamanashi, Japan. kueki@yamanashi.ac.jp
International Journal of Oral and Maxillofacial Surgery
|December 4, 2012
Summary
This study found that using Biopex® with hydroxyapatite/poly-l-lactic acid plates after Le Fort I osteotomy did not significantly impact maxillary stability. Maxillary stability remained consistent regardless of Biopex® use in patients with prognathism.
Area of Science:
- Oral and Maxillofacial Surgery
- Biomaterials Science
- Orthognathic Surgery
Background:
- Le Fort I osteotomy is a common surgical procedure for correcting midface deformities.
- Maxillary stability is crucial for successful long-term outcomes after orthognathic surgery.
- The use of biomaterials like hydroxyapatite/poly-l-lactic acid (u-HA/PLLA) plates and bone graft substitutes (Biopex®) aims to enhance bone healing and stability.
Purpose of the Study:
- To retrospectively compare postoperative maxillary stability after Le Fort I osteotomy.
- To evaluate the effect of using self-setting α-tricalcium phosphate (Biopex®) as an interpositional material in conjunction with u-HA/PLLA plates.
- To assess stability in patients with specific maxillomandibular discrepancies, including maxillary retrognathism and bimaxillary asymmetry.
Main Methods:
- Retrospective analysis of 45 patients undergoing Le Fort I osteotomy and bilateral sagittal split ramus osteotomy.
- Fixation using u-HA/PLLA plates.
- Patients were divided into four groups based on maxillary impaction or advancement and the use or non-use of Biopex®.
- Cephalometric parameters were measured at 1, 3, and 12 months postoperatively.
Main Results:
- Postoperative maxillary stability was comparable across all four groups.
- The use of Biopex® as an interpositional material did not demonstrate a significant effect on maxillary stability.
- Stability outcomes were consistent irrespective of whether Biopex® was used or not.
Conclusions:
- The addition of Biopex® to u-HA/PLLA fixation in Le Fort I osteotomy does not appear to influence short-term to mid-term maxillary stability.
- Maxillary stability after Le Fort I osteotomy is primarily governed by surgical technique and fixation methods, rather than the adjunctive use of Biopex®.
- Further research may explore long-term effects or specific patient subgroups where Biopex® might offer benefits.
