Related Experiment Video
Updated: May 16, 2026
11:26
Ratiometric Calcium Imaging of Individual Neurons in Behaving Caenorhabditis Elegans
Published on: February 7, 2018
A novel ratiometric emission probe for Ca2+ in living cells
Qiaoling Liu1, Wei Bian, Heping Shi
1Research Center of Environmental Science and Engineering, and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, P. R. China.
Organic & Biomolecular Chemistry
|December 4, 2012
Abstract:
A ratiometric fluorescent probe for Ca(2+) based on 1,3,4-oxadiazole derivative has been designed and developed. The probe exhibits a large Stokes shift of 202 nm and a highly selective ratiometric emission response (490/582 nm) to Ca(2+) over other metal cations. Additionally, the probe can readily reveal the changes of intracellular Ca(2+) concentration in living human umbilical vein endothelial cells.
