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New triterpenoids with cytotoxic activity from actinidia valvata
Li-Ping Qu1, Guo-Yin Zheng, Yong-Hua Su
1Department of Traditional Chinese Medicine, Changhai Hospital of Second Military Medical University, Shanghai 200433, China. lingchangquan@gmail.com.
Abstract:
Two new triterpenoids, 30-O-beta-D-glucopyranosyloxy-2alpha,3alpha,24-trihydroxyurs-12,18-diene-28-oic acid O-beta-D-glucopyranosyl ester (1) and 2alpha,3beta,3,30-tetrahydroxyurs-12,18-diene-28-oic acid O-beta-D-glucopyranosyl ester (2) were isolated from roots of Actinidia valvata Dunn. Their structures were elucidated by means of extensive spectroscopic studies. Both these two new compounds showed moderate cytotoxic activity in vitro against BEL-7402 and SMMC-7721 tumor cell line.