Related Experiment Video
Updated: May 16, 2026

The Combined Use of Transcranial Direct Current Stimulation and Robotic Therapy for the Upper Limb
Published on: September 23, 2018
An unusual effect of interferential therapy
Keramat Ullah Keramat1, Aisling Gaughran
1Department of Physiotherapy, St. Patrick's Hospital, Carrick on Shannnon, Ireland. Karamatjee@gmail.com
Abstract:
In this report, a patient with severe shoulder pain was treated with interferential currents, a commonly used modality in physiotherapy for the management of pain. He reported loss of concentration, drowsiness, decreased alertness and gait disturbance, along with analgaesia, for 4-5 h after each treatment. He was regularly taking tramadol HCl for pain relief. Endogenous opioids produced in response to interferential therapy may be excessive or may interact with the tramadol HCl and potentiate its effect. There is no published report of interferential-induced symptoms, as described above, in the authors' knowledge. The clinician using interferential currents should be aware of this possible effect.
