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Understanding the molecular sensitization for Cypress pollen and peach in the Languedoc-Roussillon area
D Caimmi1, D Barber, K Hoffmann-Sommergruber
1Département de Pneumologie, University Hospital of Montpellier, Hôpital Arnaud de Villeneuve and INSERM U657 - EA2415, Montpellier, France.
Background:
Cypress allergy is a typical winter pollinosis and the most frequent one in the South of France. Main symptoms are rhinitis, conjunctivitis, and asthma. Peach allergy is common too in Southern Europe. Allergic cross-reactions between cypress and peach have been reported, including an oral allergy syndrome. We wanted to investigate whether a cross-reactive allergen between cypress and peach might be responsible for the observed clinical association.
Methods:
We analyzed 127 patients included over a 3-month period, outside the pollen season, and we dosed specific IgE levels, for selected, individual allergens.
Results:
Patients sensitized to peach were mainly positive for the peach-nonspecific lipid-transfer protein.
Conclusions:
Profilins or thaumatins could not explain the observed clinical association between cypress and peach.
