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Leaky Scanning02:28

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...

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Related Experiment Video

Updated: May 16, 2026

Eye-tracking to Distinguish Comprehension-based and Oculomotor-based Regressive Eye Movements During Reading
05:54

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Published on: October 18, 2018

Using E-Z reader to examine word skipping during reading.

Erik D Reichle1, Denis Drieghe

  • 1Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA. reichle@pitt.edu

Journal of Experimental Psychology. Learning, Memory, and Cognition
|December 5, 2012
PubMed
Summary
This summary is machine-generated.

Readers sometimes skip words, impacting reading perception and eye movements. Simulations show skipping infrequent words increases fixation time, but the cost after skipping isn't affected by word properties.

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Last Updated: May 16, 2026

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Published on: January 10, 2014

Area of Science:

  • Cognitive Psychology
  • Computational Neuroscience
  • Oculomotor Control

Background:

  • Understanding word skipping in reading is crucial for theories of perception, cognition, and eye movement control.
  • The E-Z Reader model provides a framework for examining eye movement control during reading.

Purpose of the Study:

  • To investigate the behavioral consequences of word skipping on fixation durations using the E-Z Reader model.
  • To determine how lexical properties of upcoming and skipped words influence skipping cost.

Main Methods:

  • Simulations based on the E-Z Reader model of eye-movement control in reading.
  • Analysis of fixation durations and skipping costs in relation to word properties.

Main Results:

  • Skipping infrequent or long words leads to longer fixation durations prior to the skip (skipping cost).
  • Accidental skips due to motor errors also incur skipping cost, contrary to some previous claims.
  • The cost incurred after skipping a word is not influenced by the skipped word's properties.

Conclusions:

  • Word skipping behavior in reading is complex and influenced by multiple factors.
  • Skipping cost is modulated by upcoming word properties but not by the properties of the skipped word.
  • Further empirical research is necessary to fully understand the causal mechanisms linking word skipping and its associated costs.