Related Experiment Video
Updated: May 16, 2026

06:31
Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Obstructive fibrinous tracheal pseudomembrane.
Berna Botan Yildirim1, Aysegul Karalezli, Hatice Canan Hasanoglu
1Pulmonology Department, Etlik Ihtisas Education and Research Hospital, Ankara, Turkey. mdberna2001@yahoo.com
Journal of Bronchology & Interventional Pulmonology
|December 5, 2012
Summary
Obstructive fibrinous tracheal pseudomembrane is a rare complication of endotracheal intubation. Early diagnosis and therapeutic bronchoscopy are crucial for successful treatment and improved patient outcomes.
Area of Science:
- Pulmonology
- Critical Care Medicine
Background:
- Obstructive fibrinous tracheal pseudomembrane is a rare, life-threatening complication following endotracheal intubation.
- The underlying mechanisms of tracheal pseudomembrane formation remain poorly understood.
- Early diagnosis and prompt intervention are essential to mitigate severe consequences.
Observation:
- A case of obstructive fibrinous tracheal pseudomembrane developed one day post-extubation in a patient with a two-day intubation history.
- The pseudomembrane caused significant airway obstruction.
Findings:
- Therapeutic bronchoscopy was performed to address the tracheal pseudomembrane.
- The procedure successfully removed the obstructing lesion.
Implications:
- This case highlights the efficacy of therapeutic bronchoscopy in managing obstructive fibrinous tracheal pseudomembrane.
- Prompt bronchoscopic intervention can lead to rapid clinical improvement in affected patients.
- Further research into the pathogenesis of tracheal pseudomembranes is warranted.
Related Concept Videos
Trachea
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
The Bronchial Tree
The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
Chronic Obstructive Pulmonary Disease II: Emphysema
Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Atypical Pneumonia
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Cystic Fibrosis: Pathogenesis
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...

