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Closed versus open endotracheal suctioning in extremely low-birth-weight neonates: a randomized, crossover trial
Sabine M Pirr1, Matthias Lange, Carolin Hartmann
1Department of Pediatric Pulmonology, Allergology and Neonatology, Hanover Medical School, Hanover, Germany. Pirr.Sabine@mh-hannover.de
Insights
Closed endotracheal suctioning (CS) improved oxygenation in extremely low-birth-weight (ELBW) neonates compared to open suctioning (OS). While CS reduced hypoxemia frequency and improved oxygen saturation, further research is needed to confirm overall superiority.
Area of Science:
- Neonatal Intensive Care
- Respiratory Support
- Pediatric Critical Care
Background:
- Endotracheal suctioning is common in mechanically ventilated patients.
- Complications can arise, particularly in extremely low-birth-weight (ELBW) neonates with compromised lung function.
Purpose of the Study:
- To compare the efficacy of closed endotracheal suctioning (CS) versus open endotracheal suctioning (OS).
- To determine if CS reduces hypoxemia and bradycardia in ELBW neonates.
Main Methods:
- A randomized crossover trial involving 15 ventilated ELBW neonates.
- Both CS and OS techniques were used.
- Collected data included oxygen saturation (SpO2), heart rate (HR), blood pressure, blood gases, and procedure duration.
Main Results:
- CS significantly decreased the frequency of hypoxemia (<85%) compared to OS (0.5 vs. 1.1).
- Mean minimum SpO2 was higher with CS (87%) versus OS (84%).
- CS resulted in significantly higher mean arterial PO2 and oxygenation ratio post-procedure.
Conclusions:
- Closed suctioning demonstrates superiority in improving oxygenation values in ELBW neonates.
- Further research is necessary to establish overall superiority and guide clinical practice.
- Current recommendation is individualized administration of CS for this patient group.
Background:
Endotracheal suctioning, which is frequently necessary in mechanically ventilated patients, might cause complications, especially in patients with compromised lung function such as extremely low-birth-weight (ELBW) neonates.
Objectives:
To investigate whether closed endotracheal suctioning (CS) reduces the frequency of hypoxemia and bradycardia in ELBW neonates compared to open suctioning (OS).
Methods:
In a randomized, crossover trial, 15 ventilated ELBW neonates (mean birth weight 655 g) underwent suctioning with both techniques. Data on oxygen saturation (SpO2), heart rate (HR), arterial blood pressure, arterial blood gases, duration of the suctioning procedure and recovery time were collected. Statistical analysis was done using the SPSS t test for paired samples.
Results:
The mean frequency of hypoxemia <85% was significantly decreased (p = 0.012) during CS (0.5) versus OS (1.1). The mean minimum SpO2 was significantly higher (p = 0.012) during CS (87%) compared to OS (84%), and a significantly less steep drop in mean SpO2 (p = 0.007) (CS: -5%, OS: -8%) was found. Mean arterial PO2 (p = 0.035; CS: 59 mm Hg, OS: 53 mm Hg) and mean oxygenation ratio (p = 0.016; CS: 197, OS: 171) were significantly higher after CS. No significant differences were found in HR, incidence or duration of bradycardia, recovery time, arterial blood pressure, duration of suctioning, number of complications, or duration of hypoxemia.
Conclusion:
CS was superior to OS on oxygenation values. To prove its overall superiority, further research is required. So, in this group of patients, CS should currently be administered on an individual basis.
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