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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Zosteriform skin metastasis of lung cancer
Wen-Hao Li1, Chih-Yen Tu2, Te-Chun Hsieh3
1Department of Dermatology, China Medical University, Taichung, Taiwan.
Abstract:
Skin metastasis from internal organ malignancy has a 5% to about 10% incidence, and zosteriform metastasis is much rarer. We present the case of a 51-year-old male smoker initially given a diagnosis of right lower lung adenocarcinoma T2N3M0 who developed new-onset zosteriform skin metastasis over the right-side T3∼T5 dermatomes documented by skin biopsy specimen. The probable mechanism for this band-distributed skin metastasis is the retrograde flow of lymph after obstruction by cancer cells. Such a phenomenon may be demonstrated by lymphoscintigraphy.
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