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Published on: July 7, 2014
Oxidative stress in malaria
Sandro Percário1, Danilo R Moreira, Bruno A Q Gomes
1Oxidative Stress Research Laboratory, Institute of Biological Sciences, Federal University of Para (LAPEO/ICB/UFPA) Av. Augusto Correa, 1, Guama, Belem, Para 66075-110, Brazil. percario@ufpa.br.
Malaria affects millions globally, and understanding its pathology is key to control. This review explores oxidative stress in malaria and suggests antioxidants as a potential supportive treatment.
Area of Science:
- Infectious Diseases
- Pathophysiology
- Oxidative Stress
Background:
- Malaria is a major global health issue, causing millions of infections annually.
- Incomplete understanding of malaria's pathophysiology hinders eradication efforts.
- Oxidative stress is implicated in the disease's progression.
Purpose of the Study:
- To review oxidative stress mechanisms in malaria.
- To discuss the potential of antioxidant supplementation as an adjuvant therapy.
Main Methods:
- Literature review of studies on malaria and oxidative stress.
- Analysis of the role of antioxidants in malaria pathophysiology.
Main Results:
- Oxidative stress plays a significant role in malaria pathogenesis.
- Antioxidant supplementation shows promise as an adjunctive treatment.
Conclusions:
- Further research into antioxidant therapies for malaria is warranted.
- Targeting oxidative stress could improve malaria treatment outcomes.
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