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Rickets: Part I.

Richard M Shore1, Russell W Chesney

  • 1Department of Medical Imaging, Box 9, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Ave., Chicago, IL 60611, USA. rshore@northwestern.edu

Pediatric Radiology
|December 5, 2012
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Summary
This summary is machine-generated.

Vitamin D deficiency rickets impairs bone growth in children, remaining a global health issue despite known prevention. This review details its causes, symptoms, and controversies surrounding vitamin D sufficiency.

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Area of Science:

  • Pediatrics
  • Endocrinology
  • Nutritional Science

Background:

  • Rickets is a condition affecting bone mineralization and ossification in children's growth plates.
  • Nutritional vitamin D deficiency is the most common cause of rickets.
  • Despite effective prevention, vitamin D deficiency rickets persists globally.

Purpose of the Study:

  • To provide a comprehensive review of vitamin D deficiency rickets.
  • To cover the history, etiology, pathophysiology, and clinical/radiographical findings.
  • To discuss less common causes and differential diagnoses of rickets.

Main Methods:

  • Literature review of rickets, focusing on vitamin D deficiency.
  • Analysis of historical, etiological, and pathophysiological data.
  • Compilation of clinical and radiographical findings.

Main Results:

  • Vitamin D deficiency rickets is a significant global health problem.
  • The review details various aspects of the condition, including its causes and presentation.
  • Controversial topics such as vitamin D sufficiency levels and infant fractures are addressed.

Conclusions:

  • Vitamin D deficiency rickets requires continued attention and management strategies.
  • Understanding the etiology and pathophysiology is crucial for effective prevention and treatment.
  • Further research is needed to clarify controversies surrounding vitamin D levels and related health issues.