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Updated: May 16, 2026
11:27
Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
Gd3+ cFLFLFK conjugate for MRI: a targeted contrast agent for FPR1 in inflammation
Graeme J Stasiuk1, Helen Smith, Marzena Wylezinska-Arridge
1Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
Chemical Communications (Cambridge, England)
|December 5, 2012
Abstract:
Formyl Peptide Receptors (FPRs) are vital in the host inflammatory response, playing an important regulatory role in multiple diseases. A Gd(III) DOTA conjugate of cFLFLFK has been synthesised which targets and visualises FPR1 upon leukocytes in the inflammatory response via magnetic resonance imaging for the first time.
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