Related Experiment Video
Updated: May 16, 2026
10:24
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Pharmaceutical composition for treating macular degeneration (WO2012079419)
Shusheng Wang1, Khrishen Cunnusamy
1Tulane University, Department of Cell and Molecular Biology, LA, USA. swang1@tulane.edu
Expert Opinion on Therapeutic Patents
|December 11, 2012
Summary
A novel pharmaceutical composition using traditional Chinese medicines offers a new treatment for age-related macular degeneration (AMD). This approach may address both symptoms and root causes of wet AMD.
Area of Science:
- Ophthalmology
- Pharmacology
- Traditional Chinese Medicine
Background:
- Age-related macular degeneration (AMD) is a leading cause of vision loss.
- Wet AMD involves abnormal blood vessel growth in the retina.
- Current treatments for wet AMD have limitations.
Purpose of the Study:
- To introduce a novel pharmaceutical composition for treating age-related macular degeneration (AMD).
- To explore traditional Chinese medicine as an alternative therapeutic strategy for wet AMD.
Main Methods:
- The study focuses on a pharmaceutical composition derived from traditional Chinese medicines.
- The composition is investigated for its therapeutic potential in wet AMD.
Main Results:
- The composition is claimed to treat age-related macular degeneration (AMD).
- It potentially offers a dual approach by treating symptoms and underlying causes.
Conclusions:
- This traditional Chinese medicine-based composition presents a novel therapeutic option for wet AMD.
- It holds potential for managing this degenerative retinal disease more comprehensively.
Related Concept Videos
01:23Ophthalmic Drug Delivery Systems
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
01:27Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...