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Updated: May 16, 2026
14:49
Conducting Respiratory Oscillometry in an Outpatient Setting
Published on: April 8, 2022
Randomized controlled crossover trial of a new oscillatory device as add-on therapy for COPD
Zvi G Fridlender1, Nissim Arish, Uri Laxer
1Institute of Pulmonary Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
COPD
|December 11, 2012
Summary
A novel oscillatory device safely improved 6-minute walk (6MW) distance, pulmonary function, and quality of life in patients with moderate-to-very severe chronic obstructive pulmonary disease (COPD). Further research is recommended for this promising COPD treatment.
Area of Science:
- Respiratory Medicine
- Medical Devices
- Pulmonary Rehabilitation
Background:
- Chronic obstructive pulmonary disease (COPD) significantly impacts patient mobility and quality of life.
- Current treatments aim to improve lung function and exercise capacity in COPD patients.
- Novel devices for airway clearance and respiratory support are under investigation.
Purpose of the Study:
- To assess the safety and efficacy of a new oscillatory device for COPD management.
- To evaluate the device's impact on 6-minute walk (6MW) performance.
- To determine effects on pulmonary function and health-related quality of life (HRQOL).
Main Methods:
- A randomized, double-blind, controlled, crossover study was conducted.
- Participants received treatment with an oscillatory device or a sham device for 2-week periods, separated by washout phases.
- Outcomes measured included 6MW distance, forced vital capacity (FVC), inspiratory capacity (IC), and HRQOL questionnaires.
Main Results:
- 91% of patients showed clinically significant improvement in 6MW performance with the oscillatory device.
- The oscillatory device significantly increased 6MW distance (p < 0.001) compared to the sham device.
- Significant improvements were observed in FVC, IC, dyspnea, and mastery (HRQOL) with the oscillatory device.
Conclusions:
- The new oscillatory device is safe and well-tolerated in COPD patients.
- The device demonstrates significant benefits in improving exercise capacity, pulmonary function, and HRQOL.
- Further clinical evaluation of this oscillatory device for COPD treatment is warranted.
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