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Genetic test feedback with weight control advice: study protocol for a randomized controlled trial.

Susanne F Meisel1, Rebecca J Beeken, Cornelia H M van Jaarsveld

  • 1Health Behavior Research Centre, University College London, 1-19 Torrington Place, London WC1E 6BT, UK. susanne.meisel.09@ucl.ac.uk

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|December 11, 2012
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Summary
This summary is machine-generated.

Providing genetic test results for weight gain risk alongside advice may motivate preventive action. This study investigates the impact of genetic feedback on weight control motivation and behavior in university students.

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Area of Science:

  • Genetics
  • Behavioral Science
  • Public Health

Background:

  • Genetic testing for weight gain risk is accessible online, but its benefits and potential negative effects remain unclear.
  • Limited research exists on how genetic test feedback influences weight control strategies, despite its potential to prompt preventive behaviors.
  • Weight gain is common among university students, making this population relevant for studying weight management interventions.

Purpose of the Study:

  • To determine if providing genetic test results for weight gain susceptibility, alongside standard advice, enhances motivation for weight control.
  • To assess the impact of genetic feedback on the adoption of weight control strategies and actual weight management.
  • To explore the psychological reactions to genetic testing and its interaction with feedback conditions.

Main Methods:

  • 800 first-year university students were randomized into two groups: 'Feedback + Advice' (genetic results + weight control leaflet) and 'Advice Only'.
  • Motivation and use of weight control strategies were measured one month post-intervention.
  • Weight and body fat were measured at baseline and eight months; psychological reactions were also assessed.

Main Results:

  • Results are pending, as the study aims to provide initial data on the clinical utility of genetic feedback.
  • The study will analyze the motivational effects of genetic testing for weight gain susceptibility.
  • Interactions between feedback condition and genetic test status will be explored.

Conclusions:

  • This research aims to offer preliminary insights into the practical value of genetic test feedback for weight management and prevention.
  • The findings could inform the responsible implementation of genetic testing in public health initiatives.
  • Further research is needed to fully understand the long-term impact and clinical utility of genetic risk information for weight control.