Related Experiment Video
Updated: May 16, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
Life-saving devices reach the end of life with heart failure
Daniel D Matlock1, Lynne Warner Stevenson
1University of Colorado School of Medicine, Aurora, CO 80045, USA. Daniel.matlock@ucdenver.edu
Insights
Discussions regarding deactivating life-prolonging devices like implantable cardioverter-defibrillators (ICDs) and ventricular assist devices (VADs) are crucial for advanced heart failure patients. These conversations should be standard care before and during treatment, including end-of-life planning.
Area of Science:
- Cardiology
- Medical Ethics
- Palliative Care
Background:
- Increasing use of life-prolonging devices like implantable cardioverter-defibrillators (ICDs) and ventricular assist devices (VADs) in advanced heart failure.
- Most patients with these devices die with them in place, necessitating end-of-life care considerations.
- Clinicians must provide comprehensive care throughout the patient's therapy, including the end-of-life phase.
Purpose of the Study:
- To emphasize the importance of device deactivation discussions for patients with advanced heart failure.
- To advocate for these discussions to become the standard of care at various critical points in therapy.
- To analyze the evidence surrounding device deactivation at the end-of-life and propose improvements.
Main Methods:
- Review of current clinical practices and ethical considerations regarding device deactivation.
- Discussion of legal aspects of deactivating ICDs and VADs.
- Analysis of evidence related to end-of-life device management in heart failure patients.
Main Results:
- Device deactivation discussions are not yet standard care but are legally equivalent whether for ICDs or VADs.
- VAD disconnection has a more immediate impact on survival compared to ICD deactivation.
- There is a need for improved strategies and evidence to guide end-of-life device management.
Conclusions:
- Discussions about deactivating life-prolonging devices should be integrated into routine care for advanced heart failure patients.
- Timing of these discussions is critical: prior to implantation, during follow-ups, and as end-of-life approaches.
- Further research and standardized guidelines are needed to optimize end-of-life care for patients with cardiac devices.
Abstract:
The new millennium has seen a dramatic increase in use of potentially life-prolonging devices such as implantable cardioverter-defibrillators (ICDs) and ventricular assist devices (VADs) among patients with advanced heart failure. Most patients who receive these devices will have them in place when they die. Clinicians who care for these patients must commit through the entire course of therapy, including the end-of-life. Discussions about device deactivation should be the standard of care and this discussion should take place prior to implantation, during annual heart failure reviews, after major milestones, and when the end-of-life appears to be approaching. Turning off ICDs and turning off VADs in response to patient or proxy requests are legally the same although they may be perceived differently, as disconnection of the VAD is more likely to cause immediate death. This article discusses the evidence around device deactivation at the end-of-life and offers suggestions for improvement.
Related Concept Videos
Heart Failure VI: Adjunct Therapies
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy V: Interprofessional Care
Heart Failure V: Medical Management
Heart Failure IV: Classification and Diagnostic Evaluation
Pathophysiology of Heart Failure
