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Treatment of neurally mediated reflex syncope
Juan C Guzman1, Luciana V Armaganijan, Carlos A Morillo
1Department of Medicine, McMaster University, 237 Barton Street East, Hamilton, Ontario L8L 2X2, Canada.
Cardiology Clinics
|December 11, 2012
Summary
Vasovagal syncope (VVS), a common cause of fainting, has limited treatment evidence. This review examines nonpharmacologic and pharmacologic therapies for recurrent VVS, highlighting conflicting results and intervention strategies.
Area of Science:
- Cardiology
- Neurology
Background:
- Vasovagal syncope (VVS) is the most frequent cause of transient loss of consciousness across all age groups.
- Current evidence from randomized clinical trials on VVS treatment is limited, with varied results from tested interventions.
Purpose of the Study:
- To review existing evidence on nonpharmacologic and pharmacologic therapies for recurrent vasovagal syncope.
- To analyze treatment modalities aimed at interrupting the reflex response responsible for VVS.
Main Methods:
- Systematic review of available scientific literature.
- Analysis of randomized clinical trials and other studies assessing VVS treatments.
Main Results:
- Conflicting results have been reported for various nonpharmacologic and pharmacologic treatment strategies.
- Evidence supporting specific interventions for recurrent VVS is not definitive.
Conclusions:
- Effective treatment options for recurrent vasovagal syncope require further investigation.
- Interventions targeting the reflex arc of VVS show potential but need more robust evidence.
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