Related Experiment Video
Updated: May 16, 2026
07:36
Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
[A girl with excessive lymphadenopathy]
Dorian Kerklaan1, G C B Karen Bindels-de Heus, C M Michel Zwaan
1Sophia Kinderziekenhuis, afd. Kindergeneeskunde, Rotterdam, the Netherlands. doriankerklaan@gmail.com
Nederlands Tijdschrift Voor Geneeskunde
|December 11, 2012
Summary
A 6-year-old girl was diagnosed with B-cell precursor acute lymphoblastic leukemia after presenting with swollen lymph nodes. Peripheral blood smear revealed 86% lymphoblasts, indicating a rapid progression of the leukemia.
Area of Science:
- Pediatric Hematology
- Oncology
- Immunology
Background:
- Acute lymphoblastic leukemia (ALL) is a cancer of the blood and bone marrow.
- B-cell precursor ALL is the most common subtype in children.
Observation:
- A 6-year-old girl presented with rapidly increasing lymph node swellings over 3 days.
- Physical examination revealed generalized lymphadenopathy without other symptoms.
Findings:
- Peripheral blood smear analysis showed a high percentage of lymphoblasts (86%).
- Diagnosis confirmed as B-cell precursor acute lymphoblastic leukemia.
Implications:
- Early detection and prompt diagnosis are crucial for pediatric leukemia treatment.
- Understanding the presentation of B-cell precursor ALL aids in timely intervention.
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