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Refractory giardiasis in Spanish travellers.
Jose Muñoz Gutiérrez1, Edelweiss Aldasoro, Ana Requena
1Barcelona Centre for International Health Research (CRESIB, Hospital Clínic-Universitat de Barcelona), Barcelona, Spain. jmunozg@clinic.ub.es
Travel Medicine and Infectious Disease
|December 11, 2012
Summary
Refractory giardiasis is common in travelers treated for Giardia duodenalis infections, particularly those from Asia. This study highlights treatment challenges and strategies for persistent infections unresponsive to standard therapies.
Area of Science:
- Infectious Diseases
- Parasitology
- Travel Medicine
Background:
- Drug failure leads to persistent symptoms in imported Giardia duodenalis infections.
- Refractory giardiasis poses a significant challenge in clinical practice.
Purpose of the Study:
- To describe the prevalence of refractory giardiasis in a Spanish travel clinic.
- To discuss treatment strategies for Giardia duodenalis infections refractory to nitroimidazoles.
Main Methods:
- Retrospective study design.
- Analysis of patient data from a travel clinic.
- Review of treatment outcomes for giardiasis.
Main Results:
- High prevalence of refractory giardiasis observed.
- Infections acquired in Asia showed a higher prevalence of refractory cases.
- Nitroimidazoles were frequently ineffective.
Conclusions:
- Refractory giardiasis is a significant issue, especially for infections acquired in Asia.
- Alternative treatment strategies are needed for Giardia duodenalis infections unresponsive to nitroimidazoles.
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