Bronchial balloon occlusion in children with complex pulmonary air leaks

Claire Hathorn1, Nicole Armitage, David Wensley

  • 1Room 1C31, British Columbia Children's Hospital, 4480 Oak Street, Vancouver, BC, V6H 3V4, Canada.

Insights

Endobronchial balloon occlusion effectively manages severe pediatric pulmonary air leaks, including bronchopleural fistulae from necrotizing pneumonia. This minimally invasive technique offers a reversible option for complex cases, showing promise with rising fistula incidence.

Area of Science:

  • Pediatric Pulmonology
  • Anesthesiology
  • Thoracic Surgery

Background:

  • Pulmonary air leaks in children often stem from infection or barotrauma.
  • While severe barotrauma cases decrease due to neonatal care advances, necrotizing pneumonia incidence is rising.
  • Conservative management suffices for most air leaks, but severe cases present clinical challenges.

Observation:

  • Endobronchial balloon occlusion, an established anesthetic technique, is underutilized in pediatric complex air leak management.
  • A 12-year review analyzed six pediatric cases of complex air leaks managed with balloon occlusion.
  • The study included bronchopleural fistulae secondary to necrotizing pneumonia and intrapulmonary air leaks from barotrauma.

Findings:

  • Balloon occlusion successfully treated both bronchopleural fistula cases and half of intrapulmonary air leak cases.
  • Effectiveness was transient in two cases involving barotrauma and filamin A deficiency.
  • No serious adverse effects or complications were observed during the procedure.

Implications:

  • Endobronchial balloons serve as a valuable, non-operative adjunct for life-threatening pediatric bronchopleural fistulae and cystic lung disease.
  • This minimally invasive and reversible procedure is increasingly relevant given the rising incidence of bronchopleural fistulae.
  • The technique offers a promising therapeutic option for complex pediatric air leaks, warranting further investigation and adoption.

Related Concept Videos

Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned under...
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
The Bronchial Tree01:23

The Bronchial Tree

The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...