[Treatment of the diffuse septic peritonitis]

Area of Science:

• Surgical Infection
• Abdominal Surgery
• Medical Device Technology

Background:

• Diffuse septic peritonitis presents a significant challenge in surgical practice.
• Traditional abdominal cavity sanation methods using antiseptics like furacilin and sodium hypochlorite have limitations.
• Optimizing intra-abdominal disinfection is crucial for improving patient outcomes.

Purpose of the Study:

• To evaluate the efficacy of a novel water solution of sodium hypochlorite immobilized in gel for abdominal cavity sanation.
• To compare the outcomes of this new method against traditional antiseptic approaches in patients with diffuse septic peritonitis.

Main Methods:

• A comparative study involving 380 patients diagnosed with diffuse septic peritonitis.
• Patients were divided into two groups: traditional treatment (n=245) and novel gel-based sodium hypochlorite treatment (n=135).
• Abdominal cavity sanation was performed using either traditional antiseptics or the immobilized sodium hypochlorite gel solution.

Main Results:

• The group treated with immobilized sodium hypochlorite gel demonstrated a 10% decrease in postoperative complication rates.
• Lethality rates were reduced by 8.2% in the group utilizing the novel gel-based sanation method.
• The novel approach showed a clear benefit in reducing morbidity and mortality.

Conclusions:

• Water solution of sodium hypochlorite immobilized in gel is a more effective method for abdominal cavity sanation in diffuse septic peritonitis.
• The study suggests a standardized approach to treatment, irrespective of severity factors, favoring the novel method.
• This innovation offers a promising advancement in managing intra-abdominal infections.